Using zebrafishand mice models, Dr. Zou's research interest is to understand the factors and mechanisms which control the death, differentiation and organization of retinal photoreceptors.
Liu F, Chen J, Yu S, Raghupathy R, Liu X, Qin Y, Li C, Huang M, Liao S, Wang J, Zou J, Shu X, Tang Z, Liu M. (2015) Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish. Hum Mol Genet. 24(16):4648-59.
Poulin JF, Zou J, Drouin-Ouellet J, Kim KY, Cicchetti F, Awatramani RB. (2014) Defining midbrain dopaminergic neuron diversity by single-cell gene expression profiling. Cell Rep. 9(3):930-43.
Zou, J, Wen, Y, Yang, X, and Wei, X (2013). Spatial-temporal expressions of Crumbs and Nagie oko and their interdependence in zebrafish central nervous system during early development. Int J Dev Neurosci 31, 770-782.
Fang, W#, Bonaffini, S#, Zou, J#, Wang, X, Zhang, C, Tsujimura, T, Kawamura, S, and Wei, X. (2013). Characterization of transgenic zebrafish lines that express GFP in the retina, pineal gland, olfactory bulb, hatching gland, and optic tectum. Gene Expr Patterns 13, 150-159. #equal contributions.
Zou, J, Wang, X, and Wei, X. (2012). Crb apical polarity proteins maintain zebrafish retinal cone mosaics via intercellular binding of their extracellular domains. Dev Cell 22, 1261-1274.
Zou, J, Yang, X, and Wei, X. (2010). Restricted localization of ponli, a novel zebrafish MAGUK-family protein, to the inner segment interface areas between green, red, and blue cones. Invest Ophthalmol Vis Sci 51, 1738-1746.
Yang, X, Zou, J, Hyde, DR, Davidson, LA, and Wei, X. (2009). Stepwise maturation of apicobasal polarity of the neuroepithelium is essential for vertebrate neurulation. J Neurosci 29, 11426-11440.
Zou, J, Lathrop, KL, Sun, M, and Wei, X. (2008). Intact retinal pigment epithelium maintained by Nok is essential for retinal epithelial polarity and cellular patterning in zebrafish. J Neurosci 28, 13684-13695.
Zou J, Beermann F, Wang J, Kawakami K, Wei X. (2006). The Fugu tyrp1 promoter directs specific GFP expression in zebrafish: tools to study the RPE and the neural crest-derived melanophores. Pigment Cell Res. 19(6):615-27.
