Dr. Chen's team has conducted studies related to keratoconus etiology, finding two new variants and three high-risk SNP of VSX1 gene, which enlarged the mutation spectrum, further confirmed the trait of genetically heterozygous and provided new breakthrough for pathogenesis and theoretical foundation for early diagnosis and targeted therapy in Chinese keratoconus patients.
Yu X, Chen B, Zhang X, et al. Identification of seven novel ZNF469 mutations in keratoconus patients in a Han Chinese population. Mol Vis. 2017 Apr 28; 23: 296-305.
Chen BB, Song FW, Sun ZH, et al. Anisometropia magnitude and visual deficits in previously untreated anisometropic amblyopia. Int J Ophthalmol. 2013 Oct 18; 6(5): 606-10.
Song FW, Chen BB, Sun ZH, et al. Novel mutation c.980_983delATTA compound with c.986C>A mutation of the FRMD7 gene in a Chinese family with X-linked idiopathic congenital nystagmus. J Zhejiang Univ Sci B. 2013 Jun;14(6):479-86.
